Partners
CarboConnect®
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Centrose is now offering CarboConnect® Services to key partners. If a Structure Activity Relationship is known for your small molecule drug program or you want to enhance your drug delivery system, there is a very good chance that CarboConnect can enhance your program further. There are numerous cases where sugars dramatically influence the physical, chemical and biological properties of drugs. There are also examples where sugars attached to peptides and small molecule drugs can increase activity and/or enhance certain pharmacokinetic properties. In addition, results show subtle changes in the sugar can change the solubility, tissue uptake, PK, potency and formulation of the drug to which sugars are attached. Centrose believes that altering drugs with specialized sugars is a promising new drug development and optimization strategy. The ability to play with the large and diverse chemical space that sugars provide could circumvent the adverse side effects that your drug leads may possess.
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